--> --> -->


Sep 2023

Innovative Robotic Inspection of Pre-Filled Syringes

Innovative Robotic Inspection of Pre-Filled Syringes

The pharmaceutical industry has witnessed a remarkable surge in the use of pre-filled syringes, offering convenient and precise drug delivery for patients worldwide. As the demand for these pre-filled syringes continues to grow, the need for robust quality control and inspection processes becomes increasingly paramount. Traditional manual inspection methods have limitations in terms of efficiency, accuracy, and scalability, paving the way for innovative solutions that can meet the stringent demands of the modern pharmaceutical landscape.

Robotic inspection of pre-filled syringes is a cutting-edge technology that holds the potential to revolutionize the quality assurance process in pharmaceutical manufacturing. Robotic inspection systems offer the advantages of precision, speed, and consistent performance, addressing some of the most critical challenges associated with conventional inspection methods. This novel approach aims to enhance product safety, improve quality control, and streamline the production process, ultimately benefiting both pharmaceutical companies and, more importantly, patients.

What are the Challenges Associated with Robotic Inspection of Pre-filled Syringes?

Robotic inspection of pre-filled syringes present various challenges that are important to address to ensure the safety and quality of pharmaceutical products. Some of the key challenges associated with robotic inspection of pre-filled syringes include:

  • Fragility of syringes: Pre-filled syringes are delicate and can be prone to breakage or damage during the inspection process, especially when handled by robots. Ensuring gentle and precise manipulation by the robotic systems is crucial to avoid any product loss or compromise.
  • Contamination risk: Maintaining a sterile environment is crucial in the pharmaceutical industry. Robotic inspection systems need to be designed and maintained carefully to prevent any potential contamination from the robot itself or the inspection environment.
  • System validation and compliance: Robotic inspection systems used in the pharmaceutical industry must adhere to strict regulatory standards and guidelines. Validating the robotic inspection system and ensuring compliance with regulatory requirements can be a complex and time-consuming process.
  • Cost considerations: Implementing robotic inspection systems can involve significant upfront costs. Pharmaceutical companies must carefully evaluate the cost-effectiveness and return on investment of such systems.
  • Flexibility and adaptability: The pharmaceutical industry may introduce new products or modify existing ones over time. Robotic inspection systems must be flexible and adaptable to accommodate these changes without significant reconfiguration or reprogramming.

E-Scan RTX Robotic Test System

The E-Scan RTX platform is a fully automated system that uses MicroCurrent HVLD technology to test the container closure integrity of pre-filled syringes. It is a reliable and versatile solution that can be customized to fit your production needs.

The system uses a robotic arm to pick up syringes from a conveyor belt and rotate them through two test stations. The first station checks for needle shield defects, and the second station inspects the rest of the syringe body. The test results are automatically generated and indicate whether the syringe is passed or failed. The adjustable failure reference allows you to set the LOD (limit of detection) for the test. This means that you can customize the test to be more or less sensitive, depending on your specific requirements. After the test, the syringes are automatically loaded back to the tray or a reject tray.

Here are some specific benefits of the E-Scan RTX platform:

  • It is fully automated, which can help to improve efficiency and accuracy.
  • It uses MicroCurrent HVLD technology, which is a sensitive and reliable method for detecting leaks.
  • It is versatile and can be customized to fit your production needs.
  • It is easy to use and maintain. .

Robotic inspection of pre-filled syringes presents a promising path forward for the pharmaceutical industry, offering unprecedented levels of accuracy, efficiency, and compliance with regulatory standards. By harnessing the power of robotics, pharmaceutical companies can elevate their quality control processes, uphold their commitment to patient safety, and stay ahead in an increasingly competitive market.

pre-filled syringe leak testing, microcurrent hvld, e-scan RTX, automated inspection, container closure integrity testing.

Popular Blogs


CCIT for Pharmaceutical Package Integrity

Jul 23, 2021   |   2734

Container Closure Integrity Testing of pharmaceutical packaging ensures that the products remain intact throughout its shelf life or until it reaches the end user.

Why is Seal Integrity Testing of Medical Device Packaging Important

Jul 29, 2021   |   2472

For sterile medical devices, seal integrity testing ensures product efficacy, shelf-life stability, and microbial sterility. Airborne Ultrasound technology is a non-destructive Container Closure Integrity test method, capable of examining seal quality for defects.

A Guide to MicroCurrent HVLD Technology

Aug 05, 2021   |   2377

In the case of parenteral drug product containers, HVLD technology is ideal for CCI testing in cases where packaging is less conductive than the liquid within.

Pre-filled Syringes Leak Detection with Vacuum Decay Vs MicroCurrent HVLD Test Methods

Nov 23, 2021   |   2064

Container Closure Integrity (CCI) can be challenged using various test methods, not all of which are equally capable of detecting leaks in the package.

Evaluating Package Integrity Solutions for Vials

Nov 30, 2021   |   2063

CCI testing is a critical component of quality assurance for vials. The defects which cause a sterile vial to leak are not necessarily defects that will be detected.